Ring exchange is an elementary interaction for modeling unconventional topological matters which hold promise for efficient quantum information processing. We report the observation of four-body ring-exchange interactions and the topological properties of anyonic excitations within an ultracold atom system. A minimum toric code Hamiltonian in which the ring exchange is the dominant term, was implemented by engineering a Hubbard Hamiltonian that describes atomic spins in disconnected plaquette arrays formed by two orthogonal superlattices. The ring-exchange interactions were resolved from the dynamical evolutions in the spin orders, matching well with the predicted energy gaps between two anyonic excitations of the spin system. A braiding operation was applied to the spins in the plaquettes and an induced phase $1.00(3)pi$ in the four-spin state was observed, confirming $frac{1}{2}$-anynoic statistics. This work represents an essential step towards studying topological matters with many-body systems and the applications in quantum computation and simulation.
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