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Register a new userPotential of volatile organic compounds as markers of entrapped humans for use in urban search-and-rescue operations
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Volatile organic compounds emitted by a human body form a chemical signature capable of providing invaluable information on the physiological status of an individual and, thereby, could serve as signs-of-life for detecting victims after natural or man-made disasters. In this review a database of potential biomarkers of human presence was created on the basis of existing literature reports on volatiles in human breath, skin emanation, blood, and urine. Approximate fluxes of these species from the human body were estimated and used to predict their concentrations in the vicinity of victims. The proposed markers were classified into groups of different potential for victim detection. The major classification discriminants were the capability of detection by portable, real-time analytical instruments and background levels in urban environment. The data summarized in this review are intended to assist studies on the detection of humans via chemical analysis and accelerate investigations in this area of knowledge.
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The aim of this work was to study the effect of volatile suspended solid (VSS) and pH on volatile fatty acids (VFA) production from waste activated sludge (WAS) fermentation by means of batch tests. The final goal was to gain insights to enhance VFA stream quality, with the novelty of using WAS with high sludge retention time. Results revealed that the optimum conditions to maximize VFAs and minimize nutrients and non-VFA sCOD are a VSS concentration of 5.9 g/L and initial pH adjustment to pH 10. The WAS bacterial community structures were analysed according to Next Generation Sequencing (NGS) of 16S rDNA amplicons. The results revealed changes of bacterial phyla abundance in comparison with the batch test starting condition.
Recommended standardized procedures for determining exhaled lower respiratory nitric oxide and nasal nitric oxide have been developed by task forces of the European Respiratory Society and the American Thoracic Society. These recommendations have paved the way for the measurement of nitric oxide to become a diagnostic tool for specific clinical applications. It would be desirable to develop similar guidelines for the sampling of other trace gases in exhaled breath, especially volatile organic compounds (VOCs) which reflect ongoing metabolism. The concentrations of water-soluble, blood-borne substances in exhaled breath are influenced by: (i) breathing patterns affecting gas exchange in the conducting airways; (ii) the concentrations in the tracheo-bronchial lining fluid; (iii) the alveolar and systemic concentrations of the compound. The classical Farhi equation takes only the alveolar concentrations into account. Real-time measurements of acetone in end-tidal breath under an ergometer challenge show characteristics which cannot be explained within the Farhi setting. Here we develop a compartment model that reliably captures these profiles and is capable of relating breath to the systemic concentrations of acetone. By comparison with experimental data it is inferred that the major part of variability in breath acetone concentrations (e.g., in response to moderate exercise or altered breathing patterns) can be attributed to airway gas exchange, with minimal changes of the underlying blood and tissue concentrations. Moreover, it is deduced that measured end-tidal breath concentrations of acetone determined during resting conditions and free breathing will be rather poor indicators for endogenous levels. Particularly, the current formulation includes the classical Farhi and the Scheid series inhomogeneity model as special limiting cases.
Isothermal rebreathing has been proposed as an experimental technique for estimating the alveolar levels of hydrophilic volatile organic compounds (VOCs) in exhaled breath. Using the prototypic test compound acetone we demonstrate that the end-tidal breath profiles of such substances during isothermal rebreathing show characteristics that contradict the conventional pulmonary inert gas elimination theory due to Farhi. On the other hand, these profiles can reliably be captured by virtue of a previously developed mathematical model for the general exhalation kinetics of highly soluble, blood-borne VOCs, which explicitly takes into account airway gas exchange as major determinant of the observable breath output. This model allows for a mechanistic analysis of various rebreathing protocols suggested in the literature. In particular, it clarifies the discrepancies between in vitro and in vivo blood-breath ratios of hydrophilic VOCs and yields further quantitative insights into the physiological components of isothermal rebreathing.
Unmanned Aerial Vehicles (UAVs) equipped with bioradars are a life-saving technology that can enable identification of survivors under collapsed buildings in the aftermath of natural disasters such as earthquakes or gas explosions. However, these UAVs have to be able to autonomously navigate in disaster struck environments and land on debris piles in order to accurately locate the survivors. This problem is extremely challenging as pre-existing maps cannot be leveraged for navigation due to structural changes that may have occurred. Furthermore, existing landing site detection algorithms are not suitable to identify safe landing regions on debris piles. In this work, we present a computationally efficient system for autonomous UAV navigation and landing that does not require any prior knowledge about the environment. We propose a novel landing site detection algorithm that computes costmaps based on several hazard factors including terrain flatness, steepness, depth accuracy, and energy consumption information. We also introduce a first-of-a-kind synthetic dataset of over 1.2 million images of collapsed buildings with groundtruth depth, surface normals, semantics and camera pose information. We demonstrate the efficacy of our system using experiments from a city scale hyperrealistic simulation environment and in real-world scenarios with collapsed buildings.
This work establishes COMPRA, a compact and reactive autonomy framework for fast deployment of MAVs in subterranean Search-and-Rescue missions. A COMPRA-enabled MAV is able to autonomously explore previously unknown areas while specific mission criteria are considered e.g. an object of interest is identified and localized, the remaining useful battery life, the overall desired exploration mission duration. The proposed architecture follows a low-complexity algorithmic design to facilitate fully on-board computations, including nonlinear control, state-estimation, navigation, exploration behavior and object localization capabilities. The framework is mainly structured around a reactive local avoidance planner, based on enhanced Potential Field concepts and using instantaneous 3D pointclouds, as well as a computationally efficient heading regulation technique, based on contour detection on an instantaneous camera stream. Those techniques decouple the collision-free path generation from the dependency of a global map and are capable of handling imprecise localization occasions. Field experimental verification of the overall architecture is performed in relevant unknown GPS-denied environments.
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