We demonstrate the occurrence of permanent spikes using the Lemaitre-Tolman-Bondi models, chosen because the solutions are exact and can be analyzed by qualitative dynamical systems methods. Three examples are given and illustrated numerically. The third example demonstrates that spikes can form directly in the matter density, as opposed to indirectly in previous studies of spikes in the Kasner regime. Spikes provide an alternative general relativistic mechanism for generating exceptionally large structures observed in the Universe.