We construct a loop induced seesaw model in a TeV scale theory with gauged U(1)_{B-L} symmetry. Light neutrino masses are generated at two-loop level and right-handed neutrinos also obtain their masses by one-loop effect. Multi-component Dark Matters (DMs) are included in our model due to the remnant discrete symmetry after the B-L symmetry breaking and the Z_2 parity which is originally imposed to the model. We investigate the multi-component DM properties, in which we have two fermionic DMs with different mass scales, O(10) GeV and O(100-1000) GeV. The former mass corresponds to the lightest right-handed neutrino mass induced by the loop effect, although the latter one to the SM gauge singlet fermion. We show each of the DM annihilation processes and compare to the the observation of relic abundance, together with the constraints of Lepton Flavor Violation (LFV) and active neutrino masses. Moreover we show that our model has some parameter region allowed by the direct detection result reported by XENON100, and it is possible to verify the model by the future XENON experiment.