The fermion mass textures are discussed in the context of F-theory SU(5) GUT. The tree-level up, down and charged lepton Yukawa couplings are computed in terms of the integrals of overlapping wavefunctions at the intersection points of three matter curves. All remaining entries in the fermion mass matrices can also be reliably estimated from higher order non-renormalizable Yukawa couplings mediated by heavy string modes and/or Kaluza-Klein states.
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