Refined astrometry measurements allow us to detect large-scale deviations from isotropy through real-time observations of changes in the angular separation between sources at cosmic distances. This cosmic parallax effect is a powerful consistency test of FRW metric and may set independent constraints on cosmic anisotropy. We apply this novel general test to LTB cosmologies with off-center observers and show that future satellite missions such as Gaia might achieve accuracies that would put limits on the off-center distance which are competitive with CMB dipole constraints.
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