Prevalence of EBV in lymphoma Patients and its relationship with histopathological type at Oncology Unit – Tishreen University Hospital
published by Tishreen University
in 2018
in Medicine
and research's language is
العربية
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Abstract in English
EBV virus is a herpes virus which affects human and causes Mononucleosis
Infection and may play a role in lymphoma.
lymphoma has two types (H or NH)
This study was performed between 2016-2017 at Tishreen University Hospital –
Oncology department; we took blood samples and performed ELISA Test (Anti EBNA
IgG) to all patients with lymphoma.
57 patients (31 male 54.4% and 26 female 45.6%) with lymphoma.
Sex doesn't has statistical significance on lymphoma
25-50 year was the most age group affected by lymphoma
We have 26 patients with Hodgkin lymphoma 45.6% and 31 patient with
nonHodgkin lymphoma 54.4%
In our study EBV disease found to have a role in causing lymphoma (P=0.004) but it
doesn't cause a specific type of lymphoma (P=0.06).
We noticed a relationship between the type of Hodgkin lymphoma and EBV disease
(P=0.034) especially Nodular sclerosis and Mixed cellularity type but we didn't notice this
relationship in nonhodgkin lymphoma.
References used
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JOHN S. GREENSPAN, B.D.S., PH.D., DEBORAH GREENSPAN, B.D.S., EVELYNE T. LENNETTE, PH.D., etc. Replication of Epstein–Barr Virus within the Epithelial Cells of Oral Hairy Leukoplakia, an AIDS-Associated Lesion. N Engl J Med 1985; 313:1564-1571December 19, 1985
ALAA FADHIL ALWAN1, NIDAL KARIM AL- RAHAL2, ZEYAD AHMED SHABEEB3 . Incidence of Epstein Barr Virus infection in newly diagnosed non-Hodgkin lymphoma in the national center of hematology-single center study. Iraqi Journal of Cancer and Medical Genetics Volume 7 - Number 1 – 2014 , 21