Prevalence of EBV in lymphoma Patients and its relationship with histopathological type at Oncology Unit – Tishreen University Hospital


Abstract in English

EBV virus is a herpes virus which affects human and causes Mononucleosis Infection and may play a role in lymphoma. lymphoma has two types (H or NH) This study was performed between 2016-2017 at Tishreen University Hospital – Oncology department; we took blood samples and performed ELISA Test (Anti EBNA IgG) to all patients with lymphoma. 57 patients (31 male 54.4% and 26 female 45.6%) with lymphoma. Sex doesn't has statistical significance on lymphoma 25-50 year was the most age group affected by lymphoma We have 26 patients with Hodgkin lymphoma 45.6% and 31 patient with nonHodgkin lymphoma 54.4% In our study EBV disease found to have a role in causing lymphoma (P=0.004) but it doesn't cause a specific type of lymphoma (P=0.06). We noticed a relationship between the type of Hodgkin lymphoma and EBV disease (P=0.034) especially Nodular sclerosis and Mixed cellularity type but we didn't notice this relationship in nonhodgkin lymphoma.

References used

MUHAMMAD AZHAR, HAFEEZ UD DIN, IQBAL MUHAMMAD, SHOAIB NAIYAR HASHMI, FARHAN AKHTAR. Frequency Of Epstein-Barr Virus In Classical Hodgkin Lymphoma. Azhar. VOL 28, NO 2 (2016)<<PUBMED
JOHN S. GREENSPAN, B.D.S., PH.D., DEBORAH GREENSPAN, B.D.S., EVELYNE T. LENNETTE, PH.D., etc. Replication of Epstein–Barr Virus within the Epithelial Cells of Oral Hairy Leukoplakia, an AIDS-Associated Lesion. N Engl J Med 1985; 313:1564-1571December 19, 1985
ALAA FADHIL ALWAN1, NIDAL KARIM AL- RAHAL2, ZEYAD AHMED SHABEEB3 . Incidence of Epstein Barr Virus infection in newly diagnosed non-Hodgkin lymphoma in the national center of hematology-single center study. Iraqi Journal of Cancer and Medical Genetics Volume 7 - Number 1 – 2014 , 21

Download