Aim: To study the efficacy of collagen crosslinking on pseudophakic bullous keratopathy. Methods: Fifteen patients with pseudophakic bullous keratopathy participated in the study. Corrected visual acuity measurement, slit lamp examination, corneal clarity grading, ocular pain intensity scale and corneal thickness measurement were performed before corneal crosslinking and 1, 3 and 6month postcrosslinking. Corneal collagen crosslinking was performed after the removal of the epithelium and the application of riboflavin every 3 minutes for 30 minutes then the ultraviolet irradiation applied for 30 minutes with the application of riboflavin every 5 minutes. Results: The mean age was 65.5 year (9 females and 6 males). Corneal thickness decreased significantly after crosslinking but the visual acuity did not change significantly after crosslinking. Corneal transparency improved in the first month. Ocular pain decreased significantly in the first and third month. Conclusion: Corneal collagen cross linking is an effective and temporal procedure to decrease ocular pain for bullous keratopathy patients