This research aims to shed light on the impact of corporate governance on the performance of listed companies in Damascus Securities Exchange (2012-2016). To achieve this objective, the researcher used a hypothetical-deductive approach to formulate the hypotheses; and analyzed the financial statements of all shareholding Syrians listed companies. Results indicate that, despite of the variation in applying corporate governance between listed companies, there is a sufficient level of commitment to the principles of corporate governance. As well as, the results showed that all performance indicators effected by corporate governance principles. The results of this study provides an empirical evidence to policy makers and regulators in Syria to emphasize the importance of the continuation of Syrian companies to abide by the applying of the principles of corporate governance; as well as the need to find a unified measure corporate governance can be applied in Syria; and at the same time the need to educate the public concerning corporate governance.