Objective: To study the relationship of H. pylori infection with short stature in children with upper gastrointestinal endoscopy with dudenal biopsy with the clotest test on the antrum biopsy for three years from the beginning of 2011 until the end of 2013 and to study the relationship with Age and sex Methods: The complete records of all children admitted to the pediatric ward at Al- Assad University Hospital and upper gastrointestinal endoscopy was performed for the first time with a dudenal biopsy and a histological study with rapid urease test on the antrum biopsy during the years 2011-2012-2013. Patients were divided into two groups : the infected group and the non-infected group based on the clotest result. The differences in standard deviations of the lengths of the two groups were studied. The mean lengths were not studied because of the age difference between the two groups. Results: The number of patients in the study sample was 180 patients with ages from 6 months to 14 years. Median age was (6) years. The distribution was 95 (52.8%) males and 85 (47.2%) females. Weight loss, short stature and abdominal pain were the main reasons for endoscopy. The rate of helicobacter pyloi infection was 76 children from 180 and the distribution was 51.3% for males and 48.7% for females. There were no statistically significant differences in the distribution of infection by sex. H. pylori infection was higher in older ages. The age groups were (3-6 years) and 6-9 years the biggest. Weight loss and shortness of stature were more pronounced in the group of patients compared to non-infected patients, and there was a statistically significant difference in the standard deviation of lengths in children with H. pylori compared to noninfected patients. There were no significant statistical differences in weight or gender.