Gastroesophageal reflux is one of the most common diseases in the world and his most important symptoms is the heartburn. He requires surgical treatment in some advanced cases. The study was performed on 20 patients who underwent laparoscopic anti-reflux surgery in Al-Assad and tishreen university hospitals in Lattakia between 2011-2017 and were followed for at least six months after surgery. The analysis of the results showed a complete efficacy of this surgery in terms of absence of clinical symptoms in patients and no need for medical treatment after surgery, Absence of major complications and temporary swallowing only in 15% of cases. Comparison with other studies has shown similar results in terms of effectiveness and complications. As a result of the study, we concluded that this surgery is low risk, highly effective, and has few complications.