The phenolic compounds were extracted from leaves and flowers of Hops and grape seeds from local production by soaking with different solvents (Methanol-ethanol-alcohol and water mixture) . The polyphenols content in the methanol extracts for 100 g dry matter was 6.31 g for the grape seeds, 2.08 g for Hops leaves and 0.6 g for Hops flowers. Methanol extracts were characterized by an antioxidant activity that appeared by their ability to Reduce ions ferriques Fe+3, at a concentration of 2500 ppm, the Reducing Power was 96.45% , 67.56% for the grape seeds and Hops leaves, respectively. The methanolic extracts of grape seeds and Hops leaves at 80 ppm showed activity in scavenge free radical DPPH. was 82.04% and 40.92% respectively. The methanolic extracts of grape seeds and Hops leaves at 250 ppm gave the ability to protect linoleic acid from the oxidation process of 78.98% and 48.41%, respectively. The antioxidant activity values of the extracts were compared with standard samples of ascorbic acid and BHT.