The research aimed to identifying the relationship between the creative thinking strategies and enhancing the competitive advantage in Tishreen university. By identifying the extent of the impact of each dimensions of creative thinking strategies and the methods used to implement these strategies on the human resource characteristic and distinctive competencies. The researcher relied on the Deductive Approach and on the descriptive approach as a general method. She has distributed the questionnaire to 350 people, they are members of the teaching staff and the heads of section, who work in Tishreen university. This study has concluded to several results, the most important one was that there were significant relationship between creative thinking strategies and enhancing the competitive advantages. But this relationship is weak, because of the weakness of training programs, especially in the field of creative thinking. The researcher reviewed many important results at the end of this research, and also presented several proposals and recommendations, and the most important of it was: the need of the university to conduct training courses for their employees, especially for development creative thinking skills, and definite their employees to the important of using creative thinking strategies in their work, in order to develop their skills and knowledge as the reflect on the develop of their performance, and enhance the competitive advantages.