Determination of Captopril in Pharmaceutical Formulations Using Spectrofluorimetric Method


Abstract in English

A sensitive, simple and selective spectrofluorimetric method has been proposed for determination Captopril (CPT) in pure form and pharmaceutical preparations. This method depends on the formation of complex between Captopril and Copper (II) at pH=3.5.

References used

PARFITT K., 1999- Martindale: The Complete Drug Reference, The Pharmaceutical Press (Ph P), 720, 836
CUSHMAN D. W., CHEUNG H. S., SABO E. F., ONDETTI M. A., 1977- Design of Potent Competitive Inhibitors of Angiotensin-Converting Enzyme. Carboxyalkanoyl and Mercaptoalkanoyl Amino Acids, Biochemistry, 16, 5484- 5491
ANTAKLI S., SARKIS N., KABAWEH M., 2010- Determination of Captopril Drug by Application of 1,10- Phenanthroline in the Spectrophotometric Technique, Asian Journal of Chemistry, 22(6), 4931-3938

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