The study aimed to identify the relationship between the technical, human, and regulatory abilities, and the adoption of decision support system in the Syrian Coast Banks. The researcher used the comprehensive inventory of all the banks in the Syrian Coast style, and relied on a questionnaire for data collection, where she distributed (118) to identify a sample of workers in the studied banks. The study concluded that the technical, human and regulatory abilities, have a role on the adoption of decision support system in the Syrian Coast Banks, and the most important result was that the banks own human capital is able to adopt a decision support systems. Then some of the recommendations show up for successful adoption of decision support systems and most important are: increased interest in available regulatory abilities through the necessity of a separate unit for decision support systems directly linked to the senior management at the banks in the Syrian Coast, and let the organizational structure to flow the information easily between different departments, greater attention to human abilities available to use the decision support systems like: provision of specialized training programs for workers to use decision support system software.