published by Aِl-Baath University
in 2016
in Chemistry
and research's language is
العربية
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Abstract in English
Two ethers coumarin derivatives: 7-phenoxy -4-carboxylic
coumarin (B) and 7- (6,2-di-chloro) -4-carboxylic coumarin (C)
have been synthesized from the 7-hydroxy-4-methy coumarin
(A) as beginning compound and the copper complex [CuPPh3Cl]4
carried on the amberlyst-21 as the eco-friendly catalyst, these ethers
coumarin derivatives have an important biological properties may
be used in the treatment of breast cancer.
References used
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G. Cravotto, G.M. Nano, G. Palmisano, S. Tagliapietra, An asymmetric approach to coumarin anticoagulants via hetero-Diels– Alder cycloaddition, Tetrahedron: Asymmetry, 12, (2001), 707–709
O. Kayser, H. Kolodziej, Antibacterial Activity of Extracts and Constituents of Pelargonium sidoides and Pelargonium reniforme, Planta Med., 63, (1997) 508–510