Synthesis of dodecanoate sodium alginate and study its properties as a carrier of ibuprofen


Abstract in English

Tow compounds have been synthesised: tetra butyl ammonium alginate and dodecanoate sodium alginate ester. The synthesis of compound (1) by transferring sodium alginate to Alginic acid and then adjusted by tetra-butyl ammonium hydroxide. The compound (2) was synthesised from tetra-butyl ammonium alginate according to Fisherest erification, between tetra-butylammonium alginate and dodecanoic acid and using (Amberlyst-15) as a hetrogeneous acid catalyst, and then the product react with sodium carbonate.

References used

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HAY. I. D, UR REHMAN. Z, GHAFOOR. A, REHM. B. H. A (2010) Bacterial biosynthesisof alginates, Journal of Chemical Technology & Biotechnology , 85, 752–759
MOE. S, BRAEK. G, SMIDSROD. O (1991) Covalently crosslinked sodium alginate beads, Food Hydrocolloid,5,119-23

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