Synthesis of dodecanoate sodium alginate and study its properties as a carrier of ibuprofen
published by Aِl-Baath University
in 2016
in
and research's language is
العربية
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Abstract in English
Tow compounds have been synthesised: tetra butyl ammonium
alginate and dodecanoate sodium alginate ester.
The synthesis of compound (1) by transferring
sodium alginate to Alginic acid and then adjusted by tetra-butyl
ammonium hydroxide. The compound (2) was synthesised from
tetra-butyl ammonium alginate according to Fisherest erification,
between tetra-butylammonium alginate and dodecanoic acid and
using (Amberlyst-15) as a hetrogeneous acid catalyst, and then the
product react with sodium carbonate.
References used
PELLETIER. S, HUBRT. P, LAPICQUE. F, PAYAN. E, DELLACHERIE. E (2000) Amphiphilic derivatives of sodium alginate and hyaluronate: synthesis and hysicochemical properties of aqueous dilute solutions, Carbohydrate Polymers, 43, 343-349
HAY. I. D, UR REHMAN. Z, GHAFOOR. A, REHM. B. H. A (2010) Bacterial biosynthesisof alginates, Journal of Chemical Technology & Biotechnology , 85, 752–759