The aim of this study was to evaluate the efficacy of botulinum toxin-A (BTX-A) therapy compared with Transcutaneous Electric Nerve Stimulation(TENS) in treatment against temporomandibular disorders clinically study Twenty patients with temporomandibular disorder symptoms and signs were enrolled in the study. The patients were randomly assigned into two groups. Patients in group 1 were injected with 20 IU BTX-A in the masseter and temporal muscle in both sides , whereas patients in group 2 were treated with (TENS),the electrodes were applied on masseter and temporal muscle in both sides, time of stimulation abut 30s ,3perweek for 4 week.