This study was conducted to evaluate the effects of butyric acid alone or with Vitamins in the feed on liver enzymes activity and some minerals in serum. One hundred (100) 1-day old unsexed commercial Japanese quail chicks were studied for 42 days. The Japanese quail chicks were randomly divided into 4 groups as 25 chicks in each. The chicks were fed with starter mash which contained crude protein24% and metabolizable energy 2850 Kcal / kg up to 42 day of age.