Evaluation the role of protein KIM-1in the kidney injuries
published by Aِl-Baath University
in 2016
in
and research's language is
العربية
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Abstract in English
Kidney Injury Molecule-1 (KIM-1) is a type 1 transmembrane
glycoprotein. KIM-1 is highly up regulated in proximal tubular
cells following kidney injury. It consists of an extracellular portion,
a novel 6-cysteine immunoglobulin-like domain, 2 N-glycosylation
sites, also contains one transmembrane domain and a short
cytoplasmic domain with a conservative tyrosine phosphorylation
site.
References used
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Ichimura T, Bonventre JV, Bailly V, Wei H, Hession CA, Cate RL, SanicolaM: Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J Biol Chem273: 4135–4142, 1998