Interdental Papilla deficiency may occur due to many factors such as traumatic oral hygiene procedure, plaque associated lesions and diverging roots following orthodontic treatment. Many of invasive and non-invasive techniques have been suggested to reconstruct the deficient interdental papilla. Treatment using hyaluronic acid gel injection is the most recent non-invasive technique which characterized by its easily application as well as avoidance exposing the patient to surgical procedures. The purpose of this study was to evaluate the efficiency of repeated cross-linked hyaluronic acid gel injection in management of deficient interdental papilla at the esthetic zone after six months of treatment.