Study of Correlation of Serum Hepcidin with Iron Status Markers and Hematological Indices among Iron Deficient Anemic patients and healthy controls in Damascus : A Case-Control Study
published by Aِl-Baath University
in 2017
in
and research's language is
العربية
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Abstract in English
Hepcidin-25 is a peptide hormone plays an important role in
regulating the systematic iron homeostasis. This paper was
conducted to study the correlations of Hepcidin with some iron
status markers and red cell indices among patients with iron
deficiency anemia (IDA) and healthy controls in Damascus. Our
study comprised 20 IDA patients (Hb≤11 g/dl for men and
women,Tsat≤20% and ferritin <30 ng/dl) and 10 healthy non
IDA controls. Complete hemogram was performed, iron status
markers (serum iron, total iron binding capacity and ferritin)
were measured and transferrin saturation was calculated .
References used
CAMASCHELLA, C. 2013. Iron and hepcidin: a story of recycling and balance. ASH Education Program Book , 2013(1),1-8
SCHMIDT, P.J. 2015.Regulation of iron metabolism by hepcidin under conditions of inflammation. Journal of Biological Chemistry,)31(292 , 18975-18983
MICHELS, K., et al. 2015. Hepcidin and host defense against infectious diseases. PLoS Pathog, 11(8), e1004998