The investigation was conducted during 2013-2014 in Al-Moroj - Baniyas - Tartous. The effect of grafting cucumber (Hybrid Amir F1 and Potenza F1) on (TZ 148 F1) rootstock on growth and production was studied. The experiment contained 4 treatments (ungrafted Amir F1 and Potenza F1, and grafted ones on Cucurbita hybrid). The results showed that grafted cucumber (Amir F1) on (TZ 148 F1) was significantly superior to other treatments in leaf area (15368.79 cm2.plant-1) and total production (21.58 kg .m-2). Grafting cucumber (Potenza F1) on (TZ148 F1) leaded to a significant decrease in each of plant height (113.25 cm), number of secondary branches (7.5 branch . plant-1), number of female flowers (94.13 flower . plant-1), number of fruits (38.13 fruit . plant-1) and total production (14.61 kg .m-2). The earliness in grafted cucumber (Amir F1 and Potenza F1) on (TZ 148 F1) (0.19 and 0.28 kg .m-2 respectively) was significantly decreased compared to ungrafted plants (0.43 and 0.54 kg .m-2 respectively). Grafting on (TZ 148 F1) didn't affected the fruit qualitative characteristics.