The study was conducted to evaluate the efficiency of Pseudomonas chlororaphis MA342, Serratia plymuthica HRO-C48K, Bacillus subtillis B2g, B. subtillis FZB27 to induce systemic resistance in Tomato plants against Cucumber mosaic virus (CMV) under greenhouse conditions. Tomato seeds submerged in suspension of Pseudomonas chlororaphis MA342, Serratia plymuthica HRO-C48, Bacillus subtillis B2g and B. subtillis FZB27 9×109cfu . plants emerged from these seed were inoculated with CMV after 10 days of planting. The time of beginning symptoms was recorded, Disease incidence, disease severity, area under disease progress curve AUDPC, progress of infection disease degrees during the study period were calculated using virtual symptoms . pyroxidas enzyme activity was determined, Some growth parameters such as Plant height, foliage fresh weight, root fresh weight , foliage dry weight, root dry weight were observed after 30 DAI. Results of this study showed that seed treatment with Pseudomonas chlororaphis MA342, Serratia .plymuthica HRO-C48, Bacillus subtillis B2g, B. subtillis FZB27 significantly decreased the diseases incidence on treated and inculated plants which ranged between 40% - 66.66% ,compared with un treated and inculated control 93.33% Without the presence of significant differences between the bacterial treatments. significantly decreased the diseases severity on treated plants which ranged between 45.53 %- 62.2% compared with inculated and un treated control 88.86% .Without the presence of significant differences between the bacterial treatments. Peroxidas activity on treated plants increased by Compared with untreated plants. Seed treatments with bacteria significantly increased the plant growth. The plant height , fresh and dry weight of foliage, fresh and dry weight of root on treated plants were significantly higher than those of inculated and un-treated plants according to LSD 5%.where bacteria reduced the rate of stunting and the rate of decline mild and dry weight of foliage and mild and dry weight of the root occurring due to infection with the Cucumber mosaic virus (CMV).