It was used in this study (15) of the female mice . They were divided into three groups : control , and two experimental groups (five mice in each group) .The control group was given distilled water, while the first experimental group was received only Paraben daily ( 250 mg / kg of body weight). As the second experimental group was received daily together of Paraben and aqueous ginger extract ( 250 mg / kg of paraben and 250 mg / aqueous ginger extract ) for (18 ) day .