The present study was performed on blood samples belong to 15 patients( 12 males,3 females) infected with cutaneous leishmaniasis, and their healing was also proved after submitting local treatment. Study tests were performed on 2 stages, the first after infection, and the second two months at least after healing. Every patient was subject of the following tests: total, and differential white blood cells count and hematocrit value. In addition ,a study of the morphological changes of white blood cells was conducted.