Association of Hepatitis B and HLA Class I in Syrian Population


Abstract in English

The possible correlation between HLA system and various course of hepatitis B has been studied in 346 subjects: 277 normal subjects, 27 HBsAg+ patients, 21 post hepatitis B liver cirrhosis patients, and 21 liver cirrhosis without previous HBV infection patients. Increased frequencies of A23, B21, B51 found in HBsAg+, A28, B55 in post HBV cirrhosis, and higher frequency of B35 in normal subjects.

References used

SCHWARTZ B. D.: The human Major histocompatibility human leukocyte antigen (HLA) complex. Basic and clinical Immunology Librairie du Liban, Beirut 1991; 45:59
BROSTOFF J., SCADDING G. K., MALE, D. K., ROITT I. M. : Clinical Immunology HLA and Disease. Gower Medical Publishing, London 1991; 2.1 : 2.13
MAUDSLEY d. j., POUND J. D. Modulation of MHC antigen expression by viruses and oncogenes. Immunol Today. 1991; 12: 429- 431

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