Conedensation Reaction Between ٥-Methyl-٣ Aminoisoxazol and Formalin


Abstract in English

A product study of the reaction of some five-membered heteroaromatic primary amines with formalin in Acetonitrile was made: Aminols of general formula (G-NH-CH٢OH) were identified in most cases at pH (٧،٥-٩) in good yield. Reaction of ٥-methyl ٣-Aminoisoxazol with formalin under basis media (pH~٩) give the Aminal (G-NH-CH٢-NH-G).

References used

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Varma., S. R., and Kumar., D.,(١٩٩٨), Manganese Triacetate Oxidation of phenolic Schiff’s bases, Synthesis of ٢-arylbenzoxazoles, J. Heterocyclic. Chem

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