This study was conducted during the seasons 1995 and 1996 at Ninevah Horticulture Station- Iraq. On Halwani and Kamali grape cultivars. This study included four levels of foliar application of Fe-EDTA at concentrations of 0, 50, 100 and 200 ppm iron, and soil compound fertilization with NPK (30 kg N + 30 kg P2O5 + 30kg K2O/ Donum) on the two abore mentioned cultivars, and the interaction among the three studied factors (cultivars, Fe and NPK), was also evaluated. The results showed that 200ppm of iron caused a significant increase in the percentage of pollen viability, Pollen grains germination, length of Pollen tube, setting of berries, ovules fertilization, leaf chlorophyll content, single leaf area, shoot leaf area, and total leaf area per vine and leaf area per cluster. The same results were obtained by using NPK fertilization. Halwani grape CV. Was significantly superior over on the Kamali grape CV. in pollen viabilits, pollen germination, length of pollen tube, leaf chlorophyll content and the single leaf area, While the Kamali grape CV. gave the highest shoot leaf area, total leaf area per vine and leaf area per cluster. The interaction among iron, NPK and cultivars reveded that the best treatment was 200 ppm iron with NPK, which gave the best results concerning flowering, setting and vegetative growth for both the cultivars.