The sexual differences in the mechanism of analgesia induced by swimming stress in Wistar rats
published by Damascus University
in 2004
in Biology
and research's language is
العربية
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Abstract in English
We had shown that the mechanism of analgesia induced by swimming
stress in Wistar males is closely related to stress, some of the relation to this
mechanism with cortical hormones. The aims of this research is to study the
sexual differences in the mechanism of analgesia induced by swimming stress in
both male and female Wistar rats and the possibility of its relation with sexual
hormones.
The male and female show an increase in the threshold of pain as result of
swimming stress (Swimming in the water during 3 minutes, with 16 C). The
analgesia in the females was more important compared with males. The
pretreatment with naloxone led to a partial inhibition of stress- induced
analgesia in both sexes, but in males it was more important.
References used
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Averbuch M,Katzper M. (2000). Asearch for sex differences in response to analgesia.Archives of internal medeicine, December 11, 160 (22): 3424-3428
Baron S. A, Gintzler A. R, (1984). Pregnancy-induced analgesia:Effects of adrenalectomy and glucocorticoid replacement. Brain Res, 12; 321(2):341-6