Ten medicinal plants were chosen from various plants in Syria which used as spices or cooked and Syria traditional medicine. Their names Rosemary, Damask rose, Chamomile, Sumac, Silver linden, Black cumin, Thyme, Mint, Laurel and lemon balm. Moisture, yield of extraction, total phenolic content (TPC) and antioxidant activities of methanol, ethanol, acetone and aqueous extracts of medicinal plants were investigated. The TPC were measured by Folin-Ciocalteu method, and the antioxidant activity was assessed by the scavenging activity towards 2, 2′-diphenyl- 1-picryl hydrazyl (DPPH)-radical.