Study has been made on 121 patients affected by myocardial infarction ( MI ) in Damascus university hospitals whereas the patients were divided in tow groups : the first group contained 60 patients treated traditionally without captopril. the second group contained 61 patients treated traditionally and by captopril these patients were examined by Echo – Doppler during the acute phase and after six months of MI to realize the effect of captopril on contractility and function of left ventricular (LV) .