A study of the effectiveness of methyl bromide (MB) and some alternatives were carried out to determine their effects on soil sterilization, densitY of nematode and production of tomato (variety Karam) crop, under greenhouses conditions in Banias area, during 1999-2000.The treatments were as follows: MB (57g/m2), Dazomet GR 98%, organic matter + solarization (Biofumigation) and control. Results showed that the effectiveness in reducing the total nematode density were 97.5%, 66.1%, 28.8 and 0% respectively. The root knots index for Meloidogyne spp. were 0, 0.64, 0.83 and 1.83 respectively. The Bio-fumigation treatment didn't have any effect on reducing the nematode density, but increased the plant growth and yield. The crop yield were 190.67, 167.33, 185 and 157.67.kg/plot respectively and there was no significant difference between the MB and the Bio-fumigation treatments.