Determination of Tropicamed by Kinetic Spectrophotometric Method in Pharmaceutical Preparations


Abstract in English

A new, simple and sensitive kinetic spectrophotometric method has been proposed for the determination of tropicamed (TPC) in pure and pharmaceutical formulations. The method is based on oxidation TPC by potassium permanganate in strong alkaline medium (pH=12) to form green colored product with absorbance maximum at 610nm.

References used

Hardman J. G., Limbird L. E., Molinoff P. B., Ruddon R. W., 1996- The Pharmacological Basis of Therapeutics, Goodman and Gilman's, 9th edition, Mc Graw-Hill, New York, 156- 7,1635
Hardman J. G., Goodman Gilman A., Limbird L. E., 2001- The pharmacological pasis of therapeutics, 10th ed. New York: Mc Graw-Hill, 1673-1685
Delgabo J. N., Remers (editors.), W. A., 2004- Wilson and Gisvold's textbook of organic medicinal and pharmaceutical chemistry, 10th ed. New York: Lippincott-Raven Publ, 585

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