Cultivars of Medicago Sativa l.var local were planted in three locations, ten pots per location. The first location wich is the most polluted one is (Bab Toma), second polluted one is (Jeser Victoria), and the reference location is (Daria), in the west of Damascus. Temperature, relative humidity and concentrations of main pollutants in that three locations were measured. Resultes showed that air pollution decreased growth of plants, amount of chlorophyll, production of plants, number of flowers, number of pods and leaf area in comparison with reference location.