The study was conducted on six varieties of cucumber: Napleon, Ampres, Sendian, Prence, Samara and Baladi. To study the responses of these varieties to drought stress, on the seed germination and seedling growth under different Polyethylen glycol concentrations (0 control, 10 mM, 20 mM and 40 mM PEG). The results of this research showed a some varieties to its tolerance to drought stress. The varieties Ampres, Prence and samara showed more resistance to drought stress. It s indicated with increasing seed germination and growth of seedlings with the higher concentration of PEG in compared to another varieties.