Malignant Fibrous Histiocytoma in oral cavity


Abstract in English

Although malignant fibrous histiocytoma are uncommon in the oral cavity. We observed these neoplasms in jawbones in 7 cases (5 in the maxilla and 2 in the mandible) affecting males aged 24 to 51 years. Histologically the pleomorphic pattern is dominant, and all patterns are characterized by active proliferative cells, and scattered histiocytes which stained positively by CD74 and CD68 These lesions cause radiolucencies with poorly defined margins and no radiographically distinct features. Differential diagnosis must involve osteosarcoma, chondrosarcoma and fibrosarcoma . The treatmenm of choice is wide surgical excision.

References used

Asirwatham JE, Pickren JW: Inflammatory fibrous histiocytoma: Case report. Cancer 41: 1467. 1978
Belza MG, Urich H: Chondroma and malignant fibrous histiocytoma: Evidence for transformation . Cancer 58: 1082 – 1087, 1986
Dahlin DC, Unni KK, Matsuno T: Malignant fibrous histiocytoma of bone fact or fancy ? Cancer 39: 1508 – 1516, 1977

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