Solid waste management is a complex problem facing decision makers in Tartous, especially in the process of selecting appropriate of solid waste land fill sites, because of the nature of the province that rich in natural resources and high population density. There is a large number of large landfills that aren’t in convenient locations, and affect to neighboring regions environment, adversely affect to the social life in the surrounding communities. In this research we identified the criteria that will be on the basis of evaluation of the locations of these landfills to achieve environmental, social and economic conditions. GIS was used to produce maps for each classification criterion separately to evaluate the landfills according to each criterion, in order to extract information from weighted map to get the appropriate locations. The study concluded that landfills sites unrealized for the majority of the standards, and to get a map showing the optimum locations of 18 sites with combined areas doesn’t exceed 0,012% of the total study area.