Development of the nursing profession and address future shortages in the labor force depends largely on the ability to attract young people to enter it, to attract these young people, it should start to identify the important factors that influence their choice of nursing profession. The study aims to identify factors influencing choice of students for the nursing profession. Research was conducted on a sample of 250 students(first-year) in Nursing College atTishreen University. Descriptive research methodologywas followed and questionnaire to collect data was used. Most of student perceived nursing as humanitarian job, 60% of them selected nursing as their first choice. For most students (72.8%), the main reason they chose to study nursing is the desire to help others. They were mostly motivated by their parents to join nursing. Nursing College was the first source of information of nursing. Nearly half of the students made the decision to workin nursing after graduationand (40%) decided to pursue higher education,