Background :In spite of all the advances in health care and medical technology, provision of qualified health care to cancer patients remains one of the major challenges that health care professionals have to face in the next years. this study was conducted with the goal of assessing effect of nursing care on meeting cancer patient's needs at home Methods: by using quazi-experimental design, eighteen breast cancer patients receiving chemotherapy were selected (40 experimental, 40 compared). Experimental group patients received supportive psycho-educational interventions for three months, consisted of ( education, progressive muscle relaxation technique, and emotional support), while compared group patients received route nursing care in hospital. After three months the results were assessed by using supportive care needs survey (SCNS) and compared by using independent T test, mean, median. Results : the results show that more than tow third of study patients had unmet needs, first of it were about information needs and emotional needs. And after study interventions these needs were decreased for intervention group patients statistically significant compared with compared group and its priorities were changed after three months. But the interventions did not improve sexual needs meeting. Conclusion: supportive care needs can improve cancer patient needs meeting in home and hospital during chemotherapy. so we recommend ascertain supportive nursing care in hospital and homes.