the leg ulcer is the common disease, it distributes widely in the world. it affect both genders, and any age. it strongly related to the vascular diseases, its most complications are infection and contact dermatitis. the management of the ulcer is depended to the etiology, and regeneration ulcer using different drugs, the surgical procedure is rarely taking place in managements ulcers. the duration of the study was february 2010 and june 2011. the percentage of leg ulcer among patients of dermatology clinic was 0.32%, and 5% of vascular surgery patients. the main age was 48 years. the most common causes of leg ulcer was chronic venous insufficiency (34%), and arterial (22%). the majority of the complications are contact dermatitis and secondary infection. therapeutic study had included drugs helping regeneration (32 ulcer), the best result was using Mebo and Silver Leaf, the percentage of healing was approximately 99% along 8 weeks.