This study was conducted to determine the prevalence and stages of chronic kidney disease and to identify common causes of chronic kidney disease in patients as well as the study of risk factors for the disease. The study included 1314 patients have been admitted to the Department of Internal Medicine at al-Assad University Hospital in Lattakia where they were diagnosed with chronic renal disease patients at 120 of them by 9.1%. The causes of chronic kidney disease were: diabetes 41.7%; hypertension 30%; Glomerulonephritis 11.7%; obstructive uropathy 5%; and Glomerugenetic disease 3.3%; mm3.3%; polycystic kidney d isease3.3% ; idiopathic 1.7%. Chronic kidney disease stages 1; 2; 3; 4; 5; were: 10%; 21.7%; 33.3% 20%; 15% respectively. Risk factors were: advanced age (over 50) 75%; high blood sugar 53.3%; lack of blood albumin 65%; hypertension 38.3%; family history of chronic kidney disease 25%; high triglycerides and cholesterol 11.7% .