The main properties(yield of juice, total soluble solid, pH, total acidity, total sugars), some antioxisant compounds as (vitamin C, carotenoids, total phenol, anthocyanins), and antioxidant activity measured by DPPH method for some main Syrian orange cultivars (navel, valancia, blood orange, and shamouti) were investigated. The results showed that valancia was the highest in juice yield (55.16%), while navel had the highest content of carotenoids(8.68mg/100g) and the lowest one of vitamin C(31.53mg/100g). Whereas, blood orange was superior in its content of total phenolic (295.73 mg gallic acid100/g) and antioxidant activity, (74.833%) among the studied cultivars.