A Contributory Study in the Determing Role of the Serum Response Factor in the Limb Vasculature Development in Embryonic Mutant Mice


Abstract in English

Serum response factor (SRF) is a protein that regulates the transcription of several other genes. It regulates especially cardiovascular system developmental regulatory genes. This study which was based on the immunohistochemistry showed that SRF influence the brain and limb vasculature development in the mice embryo.

References used

Houdebine, L-M. (1998). La trangenése Animale et ses application. INRA Unité de différenciation cellulaire. 78352 jouy-en-josas. cedex. INRA prod.Anim.,11,81-94
Mericskay, M., Parlakian, A., Proteu, A., Dandré, F., Bonnet, J., Paulin, D. and Li, Z. (2000). An Overlapping GArG/ Octamer. Element is Required for Regulation of desmin Gene Transcription in Arterial smooth muscle cells. Labo. de Biologie moléculaire de la différenciation, univ. Denis Diderot Paris -7, case 7736 France
Sadler, T. W. (2004). Langman's Medical Embryology. Ninth Edition. Lippincotte Williames and wilkins Awolterns Kuwer company philadelpha, New York , U.S.A

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