Study of Assay Methods of Phenytoin


Abstract in English

Most epeliptic patients undergo treatment with the anticonvulsive drugs, the most important of which is phonation. The treatment may last for their life time. So it should be insured to get the right theraputic dose to reach and keep the optimal phenytoin concentration in the circulating body fluid (١٥ -٢٠ ug/ml). Althought this patient should be under control in order to avoid liver damage or the incidence of toxicity of over dose of phenytoin (as a result of long term treatment

References used

Antonand K J . Product information CEDIA phenytoin Vaughan / Version as of1997
Jan Perry A., B. Invergo, H. Wagner, T. J. Szczerba, and J. *Rateike, "An Improved Internal Surface Reversed Phase", J .Liq. Chromatogr1992
Liao. J, "Development and Application of HPLC Internal Surface Reversed Phase Packing", Fenxi Ceshi Xuebao,1996

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