Fractionated and Unfractionated Heparin During Pregnancy


Abstract in English

Clinicians are occasionally faced with the dilemma of managing pregnant patients who require ongoing anticoagulation. Examples include women with mechanical heart valves, venous thromboembolism, and chronic atrial fibrillation. Methods : A prospective study randomly assigned 33 pregnant women aged between 22 and 43 years (average; 28.4); to receive either fractionated heparin: Enoxaparin (The 1st group, n = 17) or unfractionated heparin (The second group, n=16). In both groups, patients were given heparin (fractionated or unfractionated) during the 1st trimester and last month of pregnancy, and took warfarin between the 4th and 8th month.

References used

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