This research aims at revealing the relationship between the Loneliness Scal (UCLA) and Five factors of personality Inventory (NEOFFI-S) to the sample of students of the four faculties in Damascus university ( the faculty of Education , Fine arts , Economics , and faculty of Informatics engineering) and the number of the students of the sample were 120 students . This research aims to know the differences among the sample of the research in the (UCLA) and the (NEO-FFI-S) which has been attributed to the variable of the gender and the faculty.