Synthesis of Novel Macrocyclic From Schiff Bases Based on acetylacetone and terephtaldialdehide


Abstract in English

macrocyclic hydrazone Schiff base was synthesized by reaction of succinicdihydrazide, Adipicdihydrazide with acetylacetone, adipicdihydrazide with terephtaldialdehide and sebacicdihydrazide with terephtaldialdehide.

References used

Avaji, P. G. Vinod Kumar, C. H. and Shivananda, K. N., 2009. Synthesis, spectral characterization, in-vitro microbiological evaluation and cytotoxic activities of novel macrocyclic bis hydrazone C. Eur. J. Med. Chem, V.xxx, pp.1-8
Popov, L. D. Tupolova, Yu. P. and Lukov, V. V., 2008. Transition metal complexes based on 2, 4-dihydroxyisophthalic anhydride and its functionalized derivative Russian J, V.78, pp. 2094- 2099
Pavan, F. P. Maia, P. S. Leite, S. R. A. and Deflon, V. M., 2010. Thiosemicarbazones, semicarbazones, dithiocarbazates and hydrazide/hydrazones: Anti – Mycobacterium tuberculosis activity and cytotoxicity. A. A. Eur J Med Chem, V. 45, pp. 1898-1905

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