Sugar fatty acid esters are nonionic surfactants, which are used for personal care products, cosmetic applications, and as emulsifiers for food. In recent years, enzymatic synthesis of sugar fatty acid esters is attracting keen attention as a new manufacturing method for future application. Some Reaction parameters of lipase-catalyzed synthesis of SFAE in organic solvent were optimized in a batch reactor. Optimum conditions for reaction performed were 10% (w/w of substrates) of lipase from Candida antarctica B, at 60°C. Among the solvents tested in this study, the highest yield (93%) was obtained when Aceton was used as a solvent,. The optimal sugar-to-fatty acid ratio was tested in the range from 3:1 to 1:7 and verious sugars were used. A high conversion was obtained when the ratio of Sugar: Fatty acid (1:5) and Froctuse were used as substrat, respectively.