A total of 30 water samples and 45 infected fish (carp, Cyprinus carpio) were collected from freshwater fish farm (Dam of 16 Tishreen-Lattakia) and analysed bacteriological. Macroscopic examinations of infected fish had showed the presence of haemorrhagic skin lesions with brown or red spots throughout their skin. A total of 64 Aeromonas strains were isolated. The Aeromonas isolates were distributed as follows: Aeromonas hydrophila (34, 53%), A. caviae (16, 25%), A. sobria (9, 14%) and (5, 8%) of unidentified aeromonads. Collectively, Aeromonas spp. are considered as opportunistic causative agents of human gastroenteritis and other infections. Antibiotic susceptibility tests were carried on all strains of isolated Aeromonas spp. using twenty different antibiotics by agar disk diffusion method.